Losing weight and sustaining weight loss are metabolically distinct. Increased skeletal muscle efficiency is a major cause of the persistent hypometabolism that favors weight regain. This symposium discusses the effects of weight loss on muscle, and implications for types of exercise and interventions to attenuate changes in muscle that conspire against weight maintenance.

1:30pm Moving the Goalposts: The Need for Higher Levels of Exercise to Maintain Weight Loss
John M Jakicic, PhD FTOS
2:00pm Exercise and Muscle Energetics After Weight Loss
John Dubé, PhD
2:30pm Reversing Muscle Changes After Weight Loss: Promoting Inefficiency
Michael Rosenbaum, MD